Hey Mike,
It sounds like you only have a single VM experiencing this issue. There also seems to be other VMs located on the same host that can communicate with the vDS. Assuming that's the case and without further knowledge of your configuration, I'd focus on the configuration of that VM. Is it in the same portgroup and vSS as VMs that can communicate with the vDS? Also, if it's not the same subnet where's its gateway located?
~Brandit